Scientists have discovered a possible cause of pancreatic cancer (4 photos)

A study has shown that harmful bacteria and fungi in the mouth can triple the risk of pancreatic cancer. Experts warn that poor oral hygiene increases the risk of many diseases, including cancer.





Experts at New York University Medical Center have identified bacteria that increase the risk of disease. They suggest that dangerous microorganisms from the oral cavity may enter the pancreas through saliva.

In the journal JAMA Oncology, Dr. Richard Hayes, co-author of the study, noted: "It has become abundantly clear that brushing and flossing can not only prevent gum disease but also reduce the risk of cancer."



The oral microbiome, consisting of bacteria and fungi, is being actively studied for its possible role in disease development.

Scientists have discovered for the first time a link between Candida, a yeast-like fungus that normally lives on the skin and in the body, and the development of pancreatic cancer.

The team analyzed data from two studies involving 900 Americans and determined how lifestyle and medical history influence the development of cancer.

At the beginning of the study, participants provided saliva samples. Researchers then followed the patients for approximately nine years.

They compared the DNA of bacteria and fungi in saliva samples from 445 participants with pancreatic cancer and 445 people without cancer.

Twenty-four species of bacteria and fungi were identified that could either increase or decrease the risk of pancreatic cancer. Overall, the entire group of harmful microbes increased the risk of developing pancreatic cancer by more than threefold.





Study co-author Professor Jiyong Ahn said: "By profiling bacterial and fungal populations in the oral cavity, oncologists will be able to identify those most in need of pancreatic cancer screening."

The experts noted that their findings do not yet confirm a direct link between cancer and the presence of microbes in the oral cavity.

Pancreatic cancer, known as the "silent killer" due to its hidden symptoms, claims the lives of more than 10,000 people annually.

By 2040, a sharp increase in incidence is predicted, reaching 201,000 cases.



Pancreatic cancer is often detected in its late stages due to its similarity to other diseases. If it has spread beyond the pancreas, as it does in most patients, only one in ten survives.

Since the 1990s, the incidence of pancreatic cancer in women under 25 has increased by 200%. No such trend has been observed among men. Oncologists have not yet found an explanation.

The most common symptoms include jaundice, itching, and dark urine. Other possible signs include loss of appetite, weight loss, constipation, or bloating.